[(2S,4S,5R)-2,5-diacetyloxyoxan-4-yl] acetate - Names and Identifiers
Name | β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate
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Synonyms | Amrubicin Intermediate 4 2-Deoxy-D-ribose 1,3,4-Triacetate β-D-2-Deoxy-ribopyranose Triacetate 2-Deoxy-β-D-erythro-pentopyranose Triacetate [(2S,4S,5R)-2,5-diacetyloxyoxan-4-yl] acetate β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate
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CAS | 4258-01-9
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[(2S,4S,5R)-2,5-diacetyloxyoxan-4-yl] acetate - Physico-chemical Properties
Molecular Formula | C11H16O7
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Molar Mass | 260.24054 |
Solubility | Chloroform, Toluene |
Appearance | Solid |
Color | White |
Storage Condition | Refrigerator |
Use | Intermediate |
[(2S,4S,5R)-2,5-diacetyloxyoxan-4-yl] acetate - Introduction
β-D-erythro-Pentopyranose-, 2-deoxy-, 1,3,4-triacetate (β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate) is one of the synthetic intermediates of amrubicin (Amrubicin). Its chemical formula is C13H18O8 and its molecular weight is 322.28. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate is a white to pale yellow solid. It is stable at room temperature, has good solubility, and can be dissolved in common organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate is mainly used to synthesize antitumor drug amrubicin. As an important intermediate, it plays a vital role in drug synthesis.
Preparation Method:
The preparation of β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate is completed through a multi-step reaction. Generally, starting from D-fructose, the desired intermediate is finally obtained through reaction steps such as esterification, reduction and pentose ring construction.
Safety Information:
The specific safety information about β-D-erythro-Pentopyranose, 2-deoxy-, 1,3,4-triacetate varies due to the characteristics of the chemical substance. During use and handling, relevant safety procedures should be followed and personal protective equipment should be worn. Ensure that the operating environment is well ventilated and avoid contact with skin and eyes. Consult the Material Safety Data Sheet (MSDS) and follow the instructions before using or handling the chemical. In case of unclear circumstances or concerns, it is recommended to seek professional advice and guidance.
Last Update:2024-04-09 21:54:55